All primary and secondary causes and predisposing factors need to be identified, managed, and treated. Management of pain or pruritus must be included in the initial treatment protocol. Owners should initially focus on administration of topical and/or systemic drugs. The duration of treatment may vary from 7-10 days to 30 days Most commercial topical products contain a combination of antibiotic/antifungal and glucocorticoids. The volume of ear canal in most dogs is 1 mL, and at least this volume twice daily.